CALHM1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18583
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | CAHM1,Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 1,CALHM1,FAM26C,Family with sequence similarity 26,member C,MGC39514,MGC39617,OTTHUMP00000020413,Protein FAM26C,CALHM1抗体 |
| Swissprot | Q8IU99 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human CALHM1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | CALHM1 (Calcium Homeostasis Modulator 1) is a Protein Coding gene. Diseases associated with CALHM1 include Alzheimer Disease. Among its related pathways are Taste transduction. GO annotations related to this gene include identical protein binding and voltage-gated ion channel activity. An important paralog of this gene is CALHM3.This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear. |
