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CALML6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17762

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms CAGLP,Calglandulin-like protein,CALGP,CALL6,CALML6,Calmodulin like 6,Calmodulin-like protein 6,EF-hand protein,OTTHUMP00000001117,OTTHUMP00000179025,RP1-140A9.2,CALML6抗体
    Swissprot Q8TD86
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human CALML6
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 0.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), a universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases and is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turnover and smooth muscle contraction. CALML6 (calmodulin-like 6), also known as CAGLP or CALGP, is a 181 amino acid protein that contains four EF-hand domains and shares functional similarity with CaM. Localized to both the nucleus and the cytoplasm, CALML6 is expressed in heart, prostate, ovary, thymus and bone marrow where it may regulate calcium-related events.
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