CAMK2A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19660
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Alpha CaMKII,Calcium calmodulin dependent protein kinase II,Calcium/calmodulin dependent protein kinase II alpha B subunit,Calcium/calmodulin dependent protein kinase type II alpha chain,Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha,Calcium/calmodulin-dependent protein kinase II alpha,Calcium/calmodulin-dependent protein kinase II-alpha,Calcium/calmodulin-dependent protein kinase type II subunit alpha,Calcium/calmodulin-dependent protein kinase type IIA,CaM kinase II alpha chain,CaM kinase II alpha subunit,CaM kinase II subunit alpha,CaMK II alpha subunit,CaMK-II subunit alpha,Camk2a,CAMKA,CaMKII,CaMKIINalpha,EC 2.7.11.17,KCC2A,KIAA0968,MGC123320,MGC139375,MGC155201,mKIAA0968,PK2CDD,PKCCD,R74975,zgc:112538,zgc:123320,CAMK2A抗体 |
| Swissprot | Q9UQM7 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CAMK2A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction>synapse>presynaptic cell membrane. Cell junction>synapse. Postsynaptic lipid rafts. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily.Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses.This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta.The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning.In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.Two transcript variants encoding distinct isoforms have been identified for this gene. |
