CAPN3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52137
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Calcium-activated neutral proteinase 3,calpain 3, (p94),Calpain L3,Calpain large polypeptide L3 ,Calpain p94,calpain p94, large [catalytic] subunit,calpain, large polypeptide L3,Calpain-3,CAN3,CANP 3,CANP3,CANPL3,CAPN3,LGMD 2A,LGMD2,LGMD2A,Lp82,Lp85,MGC10767,MGC11121,MGC14344,MGC4403,Muscle-specific calcium-activated neutral protease 3,muscle-specific calcium-activated neutral protease 3 large subunit,nCL-1,New calpain 1,p94,CAPN3抗体 |
| Swissprot | P20807 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human CAPN3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. |
