CAPNS1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13959
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 30K,Calcium activated neutral proteinase,Calcium activated neutral proteinase small subunit,Calcium dependent protease small subunit 1,Calcium dependent protease small subunit,Calcium-activated neutral proteinase small subunit,Calcium-dependent protease small subunit 1,Calcium-dependent protease small subunit,Calpain 4,Calpain 4 small subunit (30K),Calpain 4 small subunit,Calpain regulatory subunit,Calpain small polypeptide,Calpain small subunit 1,Calpain4,CalpainS1,CANP,CANP small subunit,CANPS,CAPN 4,CAPN S1,CAPN4,CAPNS 1,CAPNS,Capns1,CDPS,CPNS1,CSS 1,CSS1,CAPNS1抗体 |
| Swissprot | P04632 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CAPNS1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon calcium binding. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. |
Images
Western Blot analysis of K562 and NIH/3T3 cell using CAPNS1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human ovarian cancer using CAPNS1 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human brain using CAPNS1 Polyclonal Antibody at dilution of 1:60
