CARD16 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17810
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | CAR16,CARD only domain-containing protein 1,CARD only protein ,CARD16,Caspase recruitment domain family, member 16,Caspase recruitment domain-containing protein 16,Caspase-1 dominant-negative inhibitor pseudo-ICE ,Caspase-1 inhibitor COP,COP,COP1,Pseudo interleukin 1 beta converting enzyme,Pseudo interleukin-1 beta converting enzyme,Pseudo interleukin-1beta converting enzyme ,PSEUDO-ICE,CARD16抗体 |
| Swissprot | Q5EG05 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CARD16 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. |
