CASP9 (active) Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12941
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASP9,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,PPP1R56,protein phosphatase 1,regulatory subunit 56,RNCASP9,CASP9 (active)抗体 |
| Swissprot | P55211 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human CASP9 (active) |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,apoptosome,cytosol,Mitochondrion,Nucleus,Other locations:protein complex |
| Tissue specificity | Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. |
