CAST Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11022
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | BS 17,Calpain inhibitor,Calpastatin,Cast,Heart type calpastatin,ICAL,MGC9402,Sperm BS 17 component,Sperm BS-17 component,CAST抗体 |
| Swissprot | P20810 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CAST |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Endoplasmic reticulum,endoplasmic reticulum,Other locations:membrane |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
Images
Western Blot analysis of Lovo cell using CAST Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human gastic cancer using CAST Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human colon cancer using CAST Polyclonal Antibody at dilution of 1:70
