Catenin beta Monoclonal Antibody
| 规格： | / 60μL / 120μL |
| 价格： | / ￥1420 / ￥2310 |
货号：E-AB-70230
宿主: Mouse
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Beta catenin,Beta-catenin,Cadherin associated protein,Catenin (cadherin associated protein),beta 1,88kDa,Catenin beta 1,Catenin beta-1,CATNB,CHBCAT,CTNB1,CTNNB,CTNNB1,DKFZp686D02253,FLJ25606,FLJ37923,OTTHUMP00000162082,OTTHUMP00000165222,OTTHUMP00000165223,OTTHUMP00000209288,OTTHUMP00000209289,Catenin beta抗体 |
| Swissprot | P35222,Q02248,Q9WU82 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse β-catenin |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000;IHC,,1:100-1:500; |
| Concentration | 420 μg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 4A3H3 |
|---|---|
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. . |
Images
Western Blot analysis of various samples using Catenin beta Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded Human colon using Catenin beta Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse stomach using Catenin beta Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded Rat stomach using Catenin beta Monoclonal Antibody at dilution of 1:200.
