CBFA2T3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19667
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Cbfa2t3,Ccore binding factor runt domain alpha subunit 2 translocated to 3,ETO2,hMTG16,hMTG16a,hMTG16b,MTG16,MTG16,MTG8 related gene 2,MTG8 related protein MTG16a,MTG8 related protein MTG16b,MTG8-related protein 2,MTGR2,Myeloid translocation gene 8 and 16b,Myeloid translocation gene on chromosome 16 protein,Protein CBFA2T3,Zinc finger MYND domain-containing protein 4,ZMYND4,CBFA2T3抗体 |
| Swissprot | O75081 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human CBFA2T3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus>nucleolus. The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm and Nucleus>nucleoplasm. Golgi apparatus membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. |
