CCL21/6Ckine Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / ￥800 / ￥2100 |
货号：AN002390P
货期：咨询
宿主: Rabbit
反应性: M
应用: ELISA Capture/Detector
Overview
| Synonyms | TCA;Scya;Beta-Chemokine Exodus;Thymus-Derived Chemotactic Agent;6Ckine;Beta-Chemokine Exodus-2;C-C Motif Chemokine 21a;Small-Inducible Cytokine A21a;TCA4;Thymus-Derived Chemotactic Agent 4;Scya21;Scya21a;Ccl21a |
| Swissprot | P84444 |
| Source | Rabbit |
| Reactivity | Mouse |
| Immunogen | Recombinant Mouse CCL21/6Ckine protein expressed by E.coli |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CCchemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signalpeptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms whileCCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 andCXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro forthymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 showspreferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes tosecondary lymphoid organs. |
