CD106 PoLycLonaL Antibody
| 规格： | / 25ug / 100ug |
| 价格： | / ￥610 / ￥1640 |
货号：D-AB-10152L
货期：咨询
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CD106;Vcam1;Vcam-1;V-CAM 1;VascuLar ceLL adhesion protein 1;SoLubLe VascuLar CeLL Adhesion MoLecuLe-1 |
| Swissprot | P29534 |
| Source | Rabbit |
| Reactivity | Human;Mouse;Rat |
| Immunogen | Recombinant Rat CD106 protein expressed by MammaLian |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000; IHC,,1:1000-1:2000 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Storeat-20℃ Valid for12months.Avoid freeze/thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation. |
