CD107b Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70198
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | CD107 antigen like family member B,CD107 antigen-like family member B,CD107b,LAMP 2,LAMP 2C,LAMP-2,LAMP2,LAMP2,LAMPB,LGP 96,LGP110,LGP96,Lysosomal associated membrane protein 2,Lysosome associated membrane glycoprotein 2,Lysosome associated membrane protein 2,Lysosome-associated membrane glycoprotein 2,Lysosome-associated membrane protein 2,MAC3,CD107b抗体 |
| Swissprot | P13473,P17047,P17046 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse LAMP2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 450 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cytoplasmic vesicle, Endosome, Lysosome, Membrane |
| Tissue specificity | Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle (PubMed:7488019, PubMed:26856698). Isoform LAMP-2B is detected in spleen, thymus, prostate, testis, small intestine, colon, skeletal muscle, brain, placenta, lung, kidney, ovary and pancreas and liver (PubMed:7488019, PubMed:26856698). Isoform LAMP-2C is detected in small intestine, colon, heart, brain, skeletal muscle, and at lower levels in kidney and placenta (PubMed:26856698).Highest expression level in corpus callosum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Lysosomal-associated membrane protein 2 (LAMP2,synonyms: LAMPB,CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection,maintenance,and adhesion of the lysosome. Prior to posttranslational modification,LAMP2 is a ~45 kDa polypeptide. Mature,functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides. |
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CD107b Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD107b Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD107b Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat liver using CD107b Polyclonal Antibody at dilution of 1:400.
