CD109 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40372
宿主: Rabbit
反应性: H,R
应用: IHC
Overview
| Synonyms | 150 KDa TGF beta 1 binding protein,150 KDa TGF-beta-1-binding protein,7D1,8A3,Activated T cell marker CD109,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7,CD 109,CD109,CD109 antigen,CD109,CPAMD7,DKFZp762L1111,E123,FLJ38569,FLJ41966,Gov system alloantigens on platelets,p180,Platelet specific Gov antigen,Platelet-specific Gov antigen,r150,RP11 525G3.1,CD109抗体 |
| Swissprot | Q6YHK3 |
| Source | Rabbit |
| Reactivity | Human,Rat |
| Immunogen | Recombinant Human CD109 antigen protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-1:300 |
| Concentration | 0.37mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Membrane |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | CD109,also named as CPAMD7,is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets,activated T-cells,and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109. The antibody can recognize all these 4 isoforms. |
