CD156c Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70180
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | A disintegrin and metalloprotease domain 10,A disintegrin and metalloproteinase domain 10,AD 10,AD10,AD18,ADA10,ADAM 10,ADAM metallopeptidase domain 10,ADAM10,CD 156c,CD156c,CD156c antigen,CDw156,disintegrin and metalloproteinase domain containing protein 10,Disintegrin and metalloproteinase domain-containing protein 10,HsT 18717,HsT18717,Kuz,Kuzbanian,Kuzbanian protein homolog,Kuzbanian,Drosophila,homolog of,MADM,Mammalian disintegrin metalloprotease,Mammalian disintegrin-metalloprotease,RAK,CD156c抗体 |
| Swissprot | O14672,O35598,Q10743 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ADAM10 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 210 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Endomembrane system. Is localized in the plasma membrane but is predominantly expressed in the Golgi apparatus and in released membrane vesicles derived likely from the Golgi. |
| Tissue specificity | Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver.Highest expression level in testis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). |
