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CD192 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70194

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms C C chemokine receptor type 2,C C CKR 2,C-C chemokine receptor type 2,C-C CKR-2,CC chemokine receptor type 2,CC CKR 2,CC-CKR-2,CCCKR2,CCR 2,CCR-2,CCR1L,CCR2,CCR2,CCR2A,CCR2B,CCR5L,CD192,CD192 antigen,Chemokine C C motif receptor 2,Chemokine CC Motif Receptor 2,CKR 2,CKR2,CKR2A,CKR2B,CMKBR2,MCP 1 R,MCP-1-R,MCP1 RECEPTOR,MCP1R,Monocyte chemoattractant protein 1 receptor,Monocyte Chemotactic Protein 1 Receptor,Monocyte Chemotactic Protein 1 Receptor,CD192抗体
    Swissprot P41597,P51683,O55193
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse CCR2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:300-1:1000
    Concentration 1.35 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Tissue specificity Expressed by monocytes and IL2-activated NK cells.Highest expression level in leukocyte.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
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