CD19 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70252
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | Antibody deficiency due to defect in CD19,included,AW495831,B lymphocyte antigen CD19,B lymphocyte surface antigen B4,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,B4,CD19,CD19 antigen,CD19 molecule,Cd19 protein,CD19,CVID3,Differentiation antigen CD19,Leu 12,Leu-12,Leu12,MGC109570,MGC12802,T-cell surface antigen Leu-12,CD19抗体 |
| Swissprot | P15391,P25918 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse CD19 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:1000 |
| Concentration | 50 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Membrane |
| Tissue specificity | Detected on marginal zone and germinal center B cells in lymph nodes (PubMed:2463100). Detected on blood B cells (at protein level) (PubMed:2463100, PubMed:16672701).Highest expression level in spleen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CD19 is a B cell–specific molecule that controls B cell activation by complexing with the BCR. CD19 is a member of the Ig superfamily and is the dominant component for the signaling complex on B cells that includes CD21,CD81,and CD22. Humans with CD19 deficiency have reduced proliferative responses to BCR stimulation in vitro and mount impaired Ab responses to vaccination. |
