CD22 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11050
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | B cell receptor CD22 precursor,B lymphocyte cell adhesion molecule,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL CAM,BL-CAM,BLCAM,CD 22,CD22,CD22 antigen,CD22 molecule,CD22 protein,CD22,Lectin 2,Leu14,Lyb8,MGC130020,sialic acid binding Ig like lectin 2,Sialic acid binding immunoglobulin like lectin 2,Sialic acid-binding Ig-like lectin 2,SIGLEC 2,Siglec-2,SIGLEC2,T cell surface antigen Leu 14,T-cell surface antigen Leu-14,CD22抗体 |
| Swissprot | P20273 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CD22 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | B-lymphocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells. |
