CD236 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11277
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CD236,CD236R,GE,GLPC,GLPC,Glycoconnectin,Glycophorin C (Gerbich blood group),Glycophorin D,Glycophorin-C,Glycophorin-D,Glycoprotein beta,GPC,GPD,Gypc,GYPD,MGC117309,MGC126191,MGC126192,PAS 2,PAS 2',PAS-2'',Sialoglycoprotein D,GYPC抗体 |
| Swissprot | P04921 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human GYPC |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Linked to the membrane via band 4.1. |
| Tissue specificity | Glycophorin-C is expressed in erythrocytes. Glycophorin-D is ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Glycophorin C (GYPC) is an integral membrane glycoprotein.It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells.A number of glycophorin C mutations have been described.The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively.The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene.The glycophorin C protein has very little homology with glycophorins A and B.Alternate splicing results in multiple transcript variants. |
