CD27 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11055
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | CD 27,CD27,CD27 antigen,CD27 molecule,CD27,CD27L receptor,LPFS2,MGC20393,OTTHUMP00000238557,S152,T cell activation antigen CD27,T cell antivation antigen S152,T-cell activation antigen CD27,T14,TNFRSF 7,TNFRSF7,TNFSF7,Tp 55,Tp55,Tumor necrosis factor receptor superfamily member 7,CD27抗体 |
| Swissprot | P26842 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CD27 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Found in most T-lymphocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
Images
Western Blot analysis of Raji and lovo cell using CD27 Polyclonal Antibody at dilution of 1:701
Immunohistochemistry of paraffin-embedded Human colon cancer using CD27 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CD27 Polyclonal Antibody at dilution of 1:60
