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CD27 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14846

宿主: Rabbit

反应性: H

应用: WB,IHC

  • 详情
  • Overview

    Synonyms CD 27,CD27,CD27 antigen,CD27 molecule,CD27,CD27L receptor,LPFS2,MGC20393,OTTHUMP00000238557,S152,T cell activation antigen CD27,T cell antivation antigen S152,T-cell activation antigen CD27,T14,TNFRSF 7,TNFRSF7,TNFSF7,Tp 55,Tp55,Tumor necrosis factor receptor superfamily member 7,CD27抗体
    Swissprot P26842
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human CD27
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:50-1:200;
    Concentration 0.9 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Tissue specificity Found in most T-lymphocytes.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
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