CD284 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70375
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ARMD10,CD284,CD284 antigen,Homolog of Drosophila toll,hToll,TLR 4,TLR4,TLR4,TOLL,Toll like receptor 4,Toll-like receptor 4,CD284抗体 |
| Swissprot | O00206,Q9QUK6,Q9QX05 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse TLR4. |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:500-1:2000; |
| Concentration | 0.9 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.Highest expression level in leukocyte. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
Images
Western Blot analysis of various samples using CD284 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD284 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat lymph using CD284 Polyclonal Antibody at dilution of 1:1000.
客户发表文献
- 文献: Nephroprotective effect of apilarnil in lipopolysaccharide-induced sepsis through TLR4/NF-κB signaling pathway
样品类型: kidney tissue - 文献: Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats
样品类型: liver
