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CD44 Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:D-AB-10184L

货期:咨询

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms LHR, BA-1, CD44 antigen, CD44 molecule, Cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor , HCELL, HAS, HUTCH1, PGP-1, Phagocytic glycoprotein 1
    Swissprot P26051
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant Rat CD44 protein expressed by E.coli
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:1000;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane, Cell projection,
    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
    Background CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration,tumor growth and progression. CD44 is also involved in lymphocyte activation,recirculation and homing,and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.
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