CD44 Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10184L
货期:咨询
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | LHR, BA-1, CD44 antigen, CD44 molecule, Cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor , HCELL, HAS, HUTCH1, PGP-1, Phagocytic glycoprotein 1 |
Swissprot | P26051 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Rat CD44 protein expressed by E.coli |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:1000; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane, Cell projection, |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration,tumor growth and progression. CD44 is also involved in lymphocyte activation,recirculation and homing,and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications. |