CD44 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15172
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44,CD44抗体 |
| Swissprot | P16070 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CD44 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane |
| Tissue specificity | Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. |
