CD54 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14711
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,ICAM1,intercellular adhesion molecule 1 (CD54),human rhinovirus receptor,Intercellular adhesion molecule 1,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10,P3.58,Surface antigen of activated B cells,BB2,ICAM1抗体 |
| Swissprot | P05362 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human ICAM1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Images
Western Blot analysis of Raji and huvec cell using CD54 Polyclonal Antibody at dilution of 1:1150
Immunohistochemistry of paraffin-embedded Human gastic cancer using CD54 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer using CD54 Polyclonal Antibody at dilution of 1:50
