CD63 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53280
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | Lysosomal associated membrane protein 3,CD 63,CD63,CD63 antigen (melanoma 1 antigen),CD63 antigen,CD63 antigen melanoma 1 antigen,CD63 molecule,CD63,gp55,Granulophysin,LAMP 3,LAMP-3,LAMP3,LIMP,Lysosomal-associated membrane protein 3,Lysosome associated membrane glycoprotein 3,Mast cell antigen AD1,ME491,Melanoma 1 antigen,Melanoma associated antigen ME491,Melanoma associated antigen MLA1,Melanoma-associated antigen ME491,MGC72893,MLA 1,MLA1,NGA,Ocular melanoma associated antigen,Ocular melanoma-associated antigen,OMA81H,PTLGP40,Tetraspanin 30,Tetraspanin-30,Tspan 30,Tspan-30,TSPAN30,CD63抗体 |
| Swissprot | P08962 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human CD63 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Lysosome membrane. Late endosome membrane. Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
