CD68 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10239L
货期：咨询
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CD 68,CD68,CD68 antigen,CD68 molecule,CD68,DKFZp686M18236,gp11,Gp110,LAMP4,Macrophage antigen CD68 (microsialin),MACROPHAGE ANTIGEN CD68,Macrosialin,SCARD1,Scavenger receptor class D member 1 |
| Swissprot | P34810 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human CD68 protein expressed by E.coli |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:250-1:500 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane |
| Tissue specificity | Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages. |
