CDC25A Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70140
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Cdc 25a,CDC25A,CDC25A2,CDC25A2 CAG isoform,Cell division cycle 25 homolog A (S. pombe),Cell division cycle 25A,Cell division cycle 25A isoform a,Cell division cycle 25A isoform b,D9Ertd393e,Dual specificity phosphatase Cdc25A,M phase inducer phosphatase 1,M-phase inducer phosphatase 1,MGC115549,MPIP1,CDC25A抗体 |
| Swissprot | P30304,P48965,P48964 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000;IHC,,1:500-1:1000; |
| Concentration | 0.96 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Tissue specificity | Ubiquitously expressed in most developing tissue. High levels in the testis and lower levels in the ovary, particularly in germ cells. Lower levels also in kidney, liver, heart and muscle.Highest expression level in ear vesicle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CDC25A is a member of the CDC25 family of phosphatases.CDC25A is required for progression from G1 to the S phase of the cell cycle.It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups.CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.Two transcript variants encoding different isoforms have been found for this gene. |
Images
Western Blot analysis of various samples using CDC25A Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded human colon using CDC25A Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded Mouse breast cancer using CDC25A Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat brain using CDC25A Polyclonal Antibody at dilution of 1:1000.
