CDCA4 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-13140
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | CDCA 4,Cdca4,CDCA4,Cell division cycle associated 4,Cell division cycle-associated protein 4,FLJ20764,FLJ52878,Hematopoietic progenitor protein,Hepp,MGC19517,SEI 3,SEI-3/HEPP,SEI3,CDCA4抗体 |
Swissprot | Q9BXL8 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human CDCA4 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:25-1:100 |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Tissue specificity | Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes. Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon. Hardly detectable, if at all, in the brain, skeletal muscle and heart. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. |