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CDCA4 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-13140

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms CDCA 4,Cdca4,CDCA4,Cell division cycle associated 4,Cell division cycle-associated protein 4,FLJ20764,FLJ52878,Hematopoietic progenitor protein,Hepp,MGC19517,SEI 3,SEI-3/HEPP,SEI3,CDCA4抗体
    Swissprot Q9BXL8
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Synthetic peptide of human CDCA4
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:25-1:100
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes. Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon. Hardly detectable, if at all, in the brain, skeletal muscle and heart.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.
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