CDH12 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19682
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Br cadherin,BR-cadherin,Brain cadherin,CAD12_HUMAN,cadherin 12 (N cadherin 2),Cadherin 12,Cadherin 12 precursor,Cadherin 12 type 2 (N cadherin 2),Cadherin 12 type 2,Cadherin neural type 2,Cadherin-12,CDH12,CDHB,FLJ34857,N cadherin 2,N-cadherin 2,Neural type cadherin 2,Neuronal cadherin 2,CDH12抗体 |
| Swissprot | P55289 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human CDH12 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 1.74mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. |
