CDK11A/B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16328
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CDC2L2,CDC2L3,p58GTA,PITSLRE,CDK11-p46,CDK11-p58,CDK11-p110 / p58,PK58,CDK11,CLK-1,CDC2L1,p58CLK-1,CDK11-p46,CDK11-p58,p58CDC2L1,CDK11-p110,CDK11A/CDK11B抗体 |
| Swissprot | Q9UQ88,P21127 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CDK11A/CDK11B |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus,Other locations:cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle.They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved.CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain.By definition, a CDK binds a regulatory protein called a cyclin.Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase.CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases. |
