CDKL4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17783
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | CDKL4,CDKL4,Cyclin dependent kinase like 4,Cyclin-dependent kinase-like 4,EC 2.7.11.22,OTTHUMP00000164944,CDKL4抗体 |
| Swissprot | Q5MAI5 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human CDKL4 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation. |
Images
Western blot analysis of Human heart tissue lysate using CDKL4 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CDKL4 Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CDKL4 Polyclonal Antibody at dilution of 1:45(×200)
