CEACAM3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13995
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | carcinoembryonic,Carcinoembryonic antigen CGM1,Carcinoembryonic antigen gene family member 1,carcinoembryonic antigen related cell adhesion molecule 3,Carcinoembryonic antigen-related cell adhesion molecule 3,cd66 d,CD66d,CD66d antigen,CEA,CEACAM 3,CEACAM-3,Ceacam3,CEAM 3,CEAM-3,CEAM3,CEAM3,CGM1,Nonspecific cross reacting antigen,W264,W282,CEACAM3抗体 |
| Swissprot | P40198 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CEACAM3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells.The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac.It is thought to serve an important role in controlling human-specific pathogens by the innate immune system.Alternatively spliced transcript variants have been described. |
