本公司产品仅供体外研究使用,不用于临床诊断

CEBP beta Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-13143

宿主: Rabbit

反应性: H,M,R

应用: IHC,ELISA

  • 详情
  • Overview

    Synonyms AGP/EBP,C EBP beta,C/EBP beta,C/EBP related protein 2,CCAAT Enhancer Binding Protein beta,CCAAT/enhancer-binding protein beta,CEBPB,CEBPB,CRP2,IL 6DBP,IL6DBP,Interleukin 6 dependent binding protein,LAP,Liver activator protein,Liver enriched transcriptional activator,NF IL6,NFIL6,Nuclear factor NF IL6,Nuclear factor NF-IL6,SF B,SFB,Silencer factor B,TCF-5,TCF5,Transcription factor 5,CEBPB抗体
    Swissprot P17676
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human CEBPB
    Application IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution IHC,,1:50-1:200;
    Concentration 0.8 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Expressed at low levels in the lung, kidney and spleen.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
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