CELSR2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12931
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog,Cadherin EGF LAG seven-pass G-type receptor 2,Cadherin family member 10,CDHF10,CELR2,Celsr2,EGF like domain multiple 2,EGF-like protein 2,EGFL2,epidermal growth factor like 2,Epidermal growth factor-like protein 2,Flamingo homolog 3,Flamingo1,KIAA0279,MEGF3,Multiple EGF-like domains protein 3,Multiple epidermal growth factor-like domains 3,Multiple epidermal growth factor-like domains protein 3,CELSR2抗体 |
Swissprot | Q9HCU4 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human CELSR2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Tissue specificity | Highest expression in brain and testis. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. |