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CELSR2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16124

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog,Cadherin EGF LAG seven-pass G-type receptor 2,Cadherin family member 10,CDHF10,CELR2,Celsr2,EGF like domain multiple 2,EGF-like protein 2,EGFL2,epidermal growth factor like 2,Epidermal growth factor-like protein 2,Flamingo homolog 3,Flamingo1,KIAA0279,MEGF3,Multiple EGF-like domains protein 3,Multiple epidermal growth factor-like domains 3,Multiple epidermal growth factor-like domains protein 3,CELSR2抗体
    Swissprot Q9HCU4
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human CELSR2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:25-1:100
    Concentration 0.4 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Tissue specificity Highest expression in brain and testis.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
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