CFL1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40164
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | 18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18,Cofilin-1抗体 |
| Swissprot | P23528 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant human Homeobox protein Cofilin-1 protein |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus matrix. Cytoplasm>cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide. |
| Tissue specificity | Widely distributed in various tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
