CHMP1A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11080
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Charged multivesicular body protein 1a,CHM1A,CHMP1a,Chromatin modifying protein 1a,Chromatin-modifying protein 1a,hVps46 1,hVps46-1,KIAA0047,Metalloprotease 1,PCOLN3,Procollagen (type III) N endopeptidase,PRSM1,Vacuolar protein sorting 46 1,Vacuolar protein sorting-associated protein 46-1,Vps46 1,Vps46-1,CHMP1A抗体 |
| Swissprot | Q9HD42 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human CHMP1A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Endosome membrane. Nucleus matrix. The cytoplasmic form is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with the chromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized by nuclease-resistant condensed chromatin. |
| Tissue specificity | Expressed in placenta, cultured skin fibroblasts and in osteoblast cell line MG-63. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene. |
