CHRNA10 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15793
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Acetylcholine receptor,neuronal nicotinic,alpha-10 subunit,ACH10,Alpha 10 nAChR,Cholinergic receptor nicotinic alpha 10,Cholinergic receptor,neuronal nicotinic,alpha polypeptide 10,Cholinergic receptor,nicotinic,alpha polypeptide 10,CHRNA 10,CHRNA10,NACHR alpha 10,NACHR alpha-10,NACHRA10,Neuronal acetylcholine receptor protein subunit alpha 10,Neuronal acetylcholine receptor subunit alpha-10,Nicotinic acetylcholine receptor subunit alpha 10,Nicotinic acetylcholine receptor subunit alpha-10,OTTHUMP00000013620,CHRNA10抗体 |
| Swissprot | Q9GZZ6 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CHRNA10 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction>synapse>postsynaptic cell membrane. Cell membrane. |
| Tissue specificity | Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. |
