CHRNA3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15792
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | ACHA3,AChR,Cholinergic receptor neuronal nicotinic alpha polypeptide 3,Cholinergic receptor nicotinic alpha 3,Cholinergic receptor nicotinic alpha polypeptide 3,CHRNA 3,CHRNA3,LNCR2,MGC104879,NACHRA 3,NACHRA3,Neuronal acetylcholine receptor protein alpha 3 chain precursor,Neuronal acetylcholine receptor subunit alpha 3,Neuronal acetylcholine receptor subunit alpha-3,Neuronal nicotinic acetylcholine receptor alpha 3 subunit,PAOD2,CHRNA3抗体 |
Swissprot | P32297 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human CHRNA3 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell junction>synapse>postsynaptic cell membrane. Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |