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CHRNA3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-15792

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms ACHA3,AChR,Cholinergic receptor neuronal nicotinic alpha polypeptide 3,Cholinergic receptor nicotinic alpha 3,Cholinergic receptor nicotinic alpha polypeptide 3,CHRNA 3,CHRNA3,LNCR2,MGC104879,NACHRA 3,NACHRA3,Neuronal acetylcholine receptor protein alpha 3 chain precursor,Neuronal acetylcholine receptor subunit alpha 3,Neuronal acetylcholine receptor subunit alpha-3,Neuronal nicotinic acetylcholine receptor alpha 3 subunit,PAOD2,CHRNA3抗体
    Swissprot P32297
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human CHRNA3
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell junction>synapse>postsynaptic cell membrane. Cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
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