CITED4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19707
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | AU019445,AW742964,Cbp/p300 interacting transactivator 4,cbp/p300 interacting transactivator, with glu/asp rich carboxy terminal domain, 4,Cbp/p300-interacting transactivator 4,CITE4,Cited4,MRG 2,MRG-2,Mrg2,MSG1 related protein 2,MSG1-related protein 2,Transcriptional co-activator 4,CITED4抗体 |
| Swissprot | Q96RK1 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CITED4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription.This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2.Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. |
