CK14 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40480
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | CK 14, CK-14, ck14, Cytokeratin 14, Cytokeratin-14, Cytokeratin14, Dowling Meara, EBS3, EBS4, Epidermolysis bullosa simplex, K14, K1C14, Keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner, Keratin 14, Keratin, Keratin type I cytoskeletal 14, Keratin,type I cytoskeletal 14, Keratin-14,Keratin14, Koebner, Krt 14, Krt14, NFJ, type I cytoskeletal 14,CK14抗体 |
| Swissprot | P02533 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Keratin, type I cytoskeletal 14 protein |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:30000-1:100000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, Intermediate filament, Keratin, Nucleus |
| Tissue specificity | Expressed in the corneal epithelium (at protein level). Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
