CK-14 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15556
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CK 14,CK-14,ck14,Cytokeratin 14,Cytokeratin-14,Cytokeratin14,Dowling Meara,EBS3,EBS4,Epidermolysis bullosa simplex,K14,K1C14,Keratin 14 (epidermolysis bullosa simplex,Dowling-Meara,Koebner),Keratin 14,Keratin,Keratin type I cytoskeletal 14,Keratin,type I cytoskeletal 14,Keratin-14,Keratin14,Koebner,Krt 14,Krt14,NFJ,OTTHUMP00000164624,type I cytoskeletal 14,KRT14抗体 |
| Swissprot | P02533 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human KRT14 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
Images
Western Blot analysis of Mouse skin tissue using CK-14 Polyclonal Antibody at dilution of 1:1350
Immunohistochemistry of paraffin-embedded Human esophagus cancer using CK-14 Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human cervical cancer using CK-14 Polyclonal Antibody at dilution of 1:20
