CK-18 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10142
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Cell proliferation inducing gene 46 protein,Cell proliferation inducing protein 46,Cell proliferation-inducing gene 46 protein,CK 18,CK-18,CK18,CYK 18,CYK18,Cytokeratin 18,Cytokeratin endo B,Cytokeratin-18,K 18,K18,K1C18,KA18,Keratin 18,Keratin 18,type I,Keratin D,keratin,type I cytoskeletal 18,Keratin-18,Krt18,KRT18抗体 |
Swissprot | P05783 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human KRT18 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm |
Tissue specificity | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. |