CK-7 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70092
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | CK 7,CK-7,CK7,Cytokeratin 7,Cytokeratin-7,D15Wsu77e,K2C7,K2C7,K7,Keratin 7,Keratin 7,type II,Keratin type II cytoskeletal 7,Keratin,55K type II cytoskeletal,Keratin,simple epithelial,Keratin,simple epithelial type I,K7,Keratin,type II cytoskeletal 7,Keratin-7,Krt2-7,KRT7,MGC11625,MGC129731,MGC3625,Sarcolectin,SCL,Type II mesothelial keratin K7,Type-II keratin Kb7,CK-7抗体 |
| Swissprot | Q9DCV7,Q6IG12 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 7 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:500 |
| Concentration | 420 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Expressed in most simple epithelia tested including liver, lactating mammary gland, lung, kidney, stomach, duodenum, colon, oviduct, uterus, pancreas, epididymis, prostate, preputial gland and mesothelium, and in most stratified epithelia tested including dorsal skin, paw/toe, tail, tongue, cervix, forestomach, and bladder. Also expressed in Henle layer of the inner root sheath of whisker follicle.Highest expression level in urinary bladder urothelium. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9–K23,and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1–K8,and the hair keratins,Hb1–Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7. |
