CK-8 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40330
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CARD2,CK 8,CK-8,CK8,CYK8,CYKER,Cytokeratin endo A,Cytokeratin-8,DreK8,EndoA,K2C8,K2C8,K8,Keratin 8,Keratin type II cytoskeletal 8,Keratin,type II cytoskeletal 8,Keratin-8,KO,Krt 2.8,KRT8,MGC118110,MGC174782,MGC53564,MGC85764,sb:cb186,Type-II keratin Kb8,CK-8抗体 |
| Swissprot | P05787 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human type II cytoskeletal 8 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-1:200 |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic |
| Tissue specificity | Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | Cytokeratin 8 (CK8) has a molecular weight of 52.5 KDa, which belongs to the HMW (high molecular weight) B-type Cytokeratin. CK8 is mainly marked on non-squamous epithelium, thus can be used for the diagnosis of adenocarcinoma and ductal carcinoma. Generally, CK8 is not expressed in squamous cell carcinoma. It is reported that hepatocellular carcinoma mainly express CK8 and CK18. |
