CKMT2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14878
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CKMT 2,Basic-type mitochondrial creatine kinase,CKMT2,CPK,Creatine kinase mitochondrial 2,Creatine kinase mitochondrial 2 (sarcomeric),Creatine kinase S-type,creatine kinase S-type,mitochondrial,Creatine kinase,sarcomeric mitochondrial,KCRS,Mib CK,Mib-CK,mitochondrial,OTTHUMP00000147542,S-MtCK,Sarcomeric mitochondrial creatine kinase,SMTCK,CKMT2抗体 |
| Swissprot | P17540 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CKMT2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion inner membrane. |
| Tissue specificity | Sarcomere-specific. Found only in heart and skeletal muscles. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. |
Images
Western Blot analysis of Jurkat cell using CKMT2 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human gastic cancer using CKMT2 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer using CKMT2 Polyclonal Antibody at dilution of 1:60
