CLIC4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53312
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Chloride intracellular channel 4,Chloride intracellular channel 4 (mitochondrial),Chloride intracellular channel 4 like,Chloride intracellular channel protein 4,Clic4,CLIC4,CLIC4L,DKFZP566G223,FLJ38640,H1,HUH1,Intracellular chloride ion channel protein p64H1,MC3S5,mtCLIC,p64H1,CLIC4抗体 |
| Swissprot | Q9Y696 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CLIC4 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle membrane. Nucleus matrix. Cell membrane. Mitochondrion. Cell junction. Colocalized with AKAP9 at the centrosome and midbody. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain. Present in an intracellular vesicular compartment that likely represent trans-Golgi network vesicles. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential,transepithelial transport,maintenance of intracellular pH,and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels,including formation of ion channels in intracellular organelles and roles in membrane trafficking,apoptosis,and cell differentiation. |
