CNN3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10711
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Acidic calponin 3,acidic isoform,Calponin 3 acidic,Calponin 3,Calponin acidic,Calponin acidic isoform,Calponin,Calponin-3,Calponin3,CNN 3,Cnn3,CNN3,dJ639P13.2.2,OTTHUMP00000012470,OTTHUMP00000012471,CNN3抗体 |
| Swissprot | Q15417 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CNN3 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,actin cytoskeleton,Cytosol,Other locations:cell-cell adherens junction,dendritic spine,focal adhesion,neuronal cell body,postsynaptic density |
| Tissue specificity | Expressed in both non-smooth muscle tissues as well as smooth muscle tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
Images
Western Blot analysis of Human fetal kidney and fetal muscle tissue using CNN3 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CNN3 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human cervical cancer using CNN3 Polyclonal Antibody at dilution of 1:25
