CNST Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19205
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | C1orf71,CNST,CNST,Consortin,Consortin connexin sorting protein,PPP1R64,Protein phosphatase 1 regulatory subunit 64,RP11-452J6.1,CNST抗体 |
Swissprot | Q6PJW8 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Fusion protein of human CNST |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Golgi apparatus>trans-Golgi network membrane. Cytoplasmic vesicle>secretory vesicle. Located predominantly in the trans-Golgi network. Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]). |