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CNST Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19205

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms C1orf71,CNST,CNST,Consortin,Consortin connexin sorting protein,PPP1R64,Protein phosphatase 1 regulatory subunit 64,RP11-452J6.1,CNST抗体
    Swissprot Q6PJW8
    Source Rabbit
    Reactivity Human
    Immunogen Fusion protein of human CNST
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 1.2mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Golgi apparatus>trans-Golgi network membrane. Cytoplasmic vesicle>secretory vesicle. Located predominantly in the trans-Golgi network. Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).
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